5245 East Main Street | Columbus| Ohio | 43213
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PictureLeon Margolin MD PhD
Dr. Margolin sees patients with deconditioning, radicular pain, cancer pain, pelvic pain, central pain and musculoskeletal pain. He also performs image guided procedures and nerve conduction studies and EMGs. Comprehensive Pain Management Institute has been certified and  Licensed for  medication p
rescriptions for chronic of pain.

Education/Specialty Training: Dr. Margolin received his medical degree and PhD from Hebrew University of Jerusalem in Israel. He completed an internship at Staten Island University and a residency in physical medicine and rehabilitation at Albert Einstein College of Medicine in New York City. Dr. Margolin completed an accredited interventional fellowship in pain medicine at the University of Pittsburgh. He is board certified by the Accreditation Council for Graduate Medical Education (ACGME) in Pain Medicine and by the American Board of Physical Medicine and             Rehabilitation. 

Professional Highlights: Dr. Margolin received a Physician’s Recognition Award from the American Medical Association (twice 2008 and 2014) , a Resident/ Fellow Award from the American Society of Regional Anesthesia and Pain Medicine, the American College of Physicians Award, the Medical Society of Pennsylvania Award, the Pfizer Scholars in Pain Management Award from the Albert Einstein College of Medicine,  the Kaye Innovation Award from the Hebrew University of Jerusalem and a 2008, 2009, 2010 Patient Choice Award 2011 Most Compassionate Doctor Award,  2014  Top Ten Doctors Award . He is widely published in more than 30 publications including a book on degenerative joint and disk research.


Dr.Margolin Book Role of Matrix Metalloproteinases in Tissue Remodeling   

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  • Role of Matrix Metalloproteinases in Tissue Remodeling
  • Author: Leon Margolin M.D., Ph.D.
  • Publisher: VDM Verlag Dr. Müller (November 20, 2009)
  • Language: English  
  • Matrix metalloproteinases (MMP) are the key enzymes in the pathogenesis of osteoarthritis and inflammatory arthritis. This study was performed on the rat common carotid artery model. This model has better accessibility and reliable injury assessment techniques in comparison to articular cartilage. This groundbreaking study shows that MMP inhibition resulted in a significant decrease in the cell proliferation and the remodeling of the extracellular matrix up to 2½ months after the MMP injection versus untreated control group and that these effects were associated with a marked reduction in MMP-2 activity. We strongly advocate testing of non hydroxamate type matrix metalloproteinase inhibitors in larger animals and in the clinical setting for degenerative joint and disc disease. Dr. Margolin's "out of the box" thinking, original study design and sharp indepth analysis are a new important step in restenosis, aortic aneurism and metastasis research as well in developing a disease modifying agent for degenerative disc and joint disease. 
Here is a map of were Dr. Margolins office is. 
Please email us with any questions, are email is [email protected]   
©Copyright by Comprehensive Pain Management Institute LLC  
April 2015 
Leon Margolin MD Phd